The Synthesis Of A Medicinal Agent Essay - 938 Words

The Synthesis of a Medicinal Agent – Aspirin IDC 3002H – EMWH Dylan Chow 9/14/2016 Abstract: In this experiment, aspirin was synthesized from a reaction between salicylic acid and acetic anhydride. Acetic anhydride was added to salicylic acid to create a solution and phosphoric acid was added to catalyze the reaction. After the salicylic acid was fully dissolved in a boiling water bath, water would be added to decompose the remaining acetic anhydride. Through the process of filtration, aspirin crystals were collected and separated from the remaining acetic acid-water solution. Then, the product of the reaction would be weighed at 3.68 g and tested for purity. Overall, the experiment was successful in producing aspirin with little impurity. I. Introduction The purpose of the experiment is to produce common drugs from organic materials. In theory, the experiment tests the idea that the therapeutic drug aspirin can be synthesized from a reaction between salicylic acid and acetic anhydride. Because consuming pure salicylic acid, a derivative of willow bark, can caused stomach pains and be difficult to consumer due to its extremely bitter taste, producing aspirin is of great importance. Aspirin is pleasant to take orally and it only breaks down when it reaches the small intestine, causing little to no damage to the stomach. To meet the primary objective of producing aspirin, a reaction called esterification needs to be undergone. This reaction changes salicylic acidShow MoreRelatedDrug Classification System ( Atc )904 Words   |  4 Pagespharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders. Pharmaceutical drugs are often classified into groups of related drugs that have similar chemical structures, the sameRead MoreSolid Phase Of Polymer Bound 2955 Words   |  4 Pages A 1,3,4-thiadiazole library was constructed by solid-phase organic synthesis. The key step of this solid-phase synthesis involves the preparation of polymer-bound 2-amido-5-amino-1,3,4-thiadiazole resin by the cyclization of thiosemicarbazide resin using p-TsCl as the desulfurative agent, followed by the functionalization of resin by alkylation, acylation, alkylation/acylation, and Suzuki coupling reaction. Both the alkylation and acylation reactions chemoselectively occurred at the 2-amide positionRead MoreThe Consequences Of Antimicrobial Resistance In Human Pathogens907 Words   |  4 PagesThe incidences of antimicrobial resistance in human pathogens have increased at an alarming rate worldwide (Tanwar et al., 2014). Nature has been a potential source of medicinal agents for thousands of years and a notable amount of modern drugs have been isolated from natural products, many based on their use in traditional medicine. The relatively lower incidence of adverse reactions to plant preparations compared to modern conventional pharmaceuticals, coupled with their reduced cost, is encouragingRead MoreModern Medicine : The Traditional Medicine System1388 Words   |  6 PagesPlant as a source of Medicine: The traditional medicine system that involves use of medicinal plants for curing various human and animal diseases is as old as human society. Most of the people living in rural areas depend on herbal medicines for treatment of some common diseases such as cold, cough, fever, bronchitis, asthma, stomach ache and many more. This is because people in rural and semi urban areas are devoid of proper medical facilities and since plants are easily available for them, theyRead MoreMedicinal Chemsitry1138 Words   |  5 Pages Topic: what is Medicinal Chemistry in the 21st century? | Name Kambura N. 201405016 | Lecturer:B.A. RickertsF Group | TABLE OF CONTENTS 1†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Cover page 2†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Introduction: What is Medicinal chemistry? 3†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...Body: The pharmaceutical industry Global generics Chemistry in a nutshell 4†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ConclusionRead MoreCarbohydrates Case Study735 Words   |  3 Pages3.6.7. Biguanides: Biguanides are other class of oral antidiabetic agents which decreases glucose absorption from the intestine. These are the class of drugs which control all types of diabetes. These are also used to treat mild diabetes during pregnancy (Singh, 2011). The recommended first line treatment used as an insulin sensitizer is metformin and it is the only biguanide available. Widely used in elderly individuals because it effectively lowers blood glucose, has a lower risk of hypoglycemiaRead MoreEssay On Silver Nanotechnology864 Words   |  4 PagesAnti-fungicidal activities, Anticancer studies, Antiviral effects, antioxidant activity etc.6 In recent years, among these applications, antioxidant activities have attracted a great deal of attention in controlling degenerative diseas es. Antioxidant agents including enzymatic and non-enzymatic substances regulate free radical formation which are generated by reactive oxygen species (ROS), superoxide dismutase (SOD), hydrogen peroxide and hydrogen radicals. Excess free radicals generated in the bodyRead MoreAntimicrobial Potency Of Silver Nanoparticles1691 Words   |  7 PagesSilver Nanoparticles Over the course of the past several years, nanotechnology has presented itself as an exciting field with various applications in modern medicine (Xia et al., 2010). With further improvement of nanotechnology, well-regulated synthesis of noble metal nanoparticles (NPs) has attracted much attention due to their possible functions in numerous areas (Yang and Cui, 2008). Among the various metal nanoparticles (NPs), silver nanoparticles (AgNPs) are particularly interesting due toRead MoreThe Need for More Medications for Dementia967 Words   |  4 PagesCurrent medications for dementia are limited and there is a need to explore traditional medicinal system to investigate the agents that can prevent progression of memory loss or improve the existing capacity of learning and memory. Thus present study was carried out to evaluate the effects of Ayurveda drug formulations, Tinospora cordifolia (Tc) Phyllanthus emblica (Pe) with and without Ocimum sanctum (Os) on learning performance and me mory of mice. We also tried to investigate the possible mechanismsRead MoreWhat Are The Importance Of Natural Products1361 Words   |  6 Pagesstructural and chemical diversity which is incomparable by any synthetic libraries. 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